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1

Design and Testing of a Pulsatile Conditioning System for Dynamic Endothelialization of Polyphenol-Stabilized Tissue Engineered Heart Valves

Leslie Neil Sierad, Agneta Simionescu, Christopher Albers, Joseph Chen, Jordan Maivelett, Mary Elizabeth Tedder, Jun Liao, Dan T. Simionescu

Journal:

Cardiovascular Engineering and Technology

Year:

2010

Language:

english

File:

PDF, 3.56 MB

english, 2010

2

Mapping of glutaraldehyde-treated bovine pericardium and tissue selection for bioprosthetic heart valves

Dan Simionescu, Agneta Simionescu, Radu Deac

Journal:

Journal of Biomedical Materials Research Part B: Applied Biomaterials

Year:

1993

Language:

english

File:

PDF, 790 KB

english, 1993

3

Xenogenic Cues for Human Mesenchymal Stem Cell Differentiation towards a Nucleus Pulposus Cell-like Phenotype

Jeremy Mercuri, Sonny Gill, Agneta Simionescu, Dan Simionescu

Journal:

The Spine Journal

Year:

2010

Language:

english

File:

PDF, 68 KB

english, 2010

4

The performance of cross-linked acellular arterial scaffolds as vascular grafts; pre-clinical testing in direct and isolation loop circulatory models

Pennel, Timothy, Fercana, George, Bezuidenhout, Deon, Simionescu, Agneta, Chuang, Ting-Hsien, Zilla, Peter, Simionescu, Dan

Journal:

Year:

2014

Language:

english

File:

PDF, 4.79 MB

english, 2014

5

Polyphenol-Stabilized Tubular Elastin Scaffolds for Tissue Engineered Vascular Grafts

Chuang, Ting-Hsien, Stabler, Christopher, Simionescu, Agneta, Simionescu, Dan T.

Journal:

Tissue Engineering Part A

Year:

2009

Language:

english

File:

PDF, 190.65 MB

english, 2009

6

Small Noncytotoxic Carbon Nano-Onions: First Covalent Functionalization with Biomolecules

Joanna Luszczyn, Marta E. Plonska-Brzezinska, Amit Palkar, Alina T. Dubis, Agneta Simionescu, Dan T. Simionescu, Beata Kalska-Szostko, Krzysztof Winkler, Luis Echegoyen

Journal:

Chemistry - A European Journal

Year:

2010

Language:

english

File:

PDF, 757 KB

english, 2010

7

Lysine-enhanced glutaraldehyde crosslinking of collagenous biomaterials

Agneta Simionescu, Dan Simionescu, Radu Deac

Journal:

Journal of Biomedical Materials Research Part B: Applied Biomaterials

Year:

1991

Language:

english

File:

PDF, 810 KB

english, 1991

8

Detection of remnant proteolytic activities in unimplanted glutaraldehyde-treated bovine pericardium and explanted cardiac bioprostheses

Dan Simionescu, Agneta Simionescu, Radu Deac

Journal:

Journal of Biomedical Materials Research Part B: Applied Biomaterials

Year:

1993

Language:

english

File:

PDF, 975 KB

english, 1993

9

Novel capillary channel fiber scaffolds for guided tissue engineering

Qijin Lu, Agneta Simionescu, Naren Vyavahare

Journal:

Acta Biomaterialia

Year:

2005

Language:

english

File:

PDF, 437 KB

english, 2005

10

Elastin-derived peptides and TGF-β1 induce osteogenic responses in smooth muscle cells

Agneta Simionescu, Katherine Philips, Narendra Vyavahare

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 730 KB

english, 2005

11

Matrix metalloproteinases in the pathology of natural and bioprosthetic cardiac valves

Agneta Simionescu, Dan T. Simionescu, Radu F.P. Deac

Journal:

Cardiovascular Pathology

Year:

1996

Language:

english

File:

PDF, 6.24 MB

english, 1996

12

Elastin Calcification in the Rat Subdermal Model Is Accompanied by Up-Regulation of Degradative and Osteogenic Cellular Responses

Jeoung Soo Lee, Dina M. Basalyga, Agneta Simionescu, Jason C. Isenburg, Dan T. Simionescu, Narendra R. Vyavahare

Journal:

The American Journal of Pathology

Year:

2006

Language:

english

File:

PDF, 717 KB

english, 2006

13

Osteogenic Responses in Fibroblasts Activated by Elastin Degradation Products and Transforming Growth Factor-β1: Role of Myofibroblasts in Vascular Calcification

Agneta Simionescu, Dan T. Simionescu, Narendra R. Vyavahare

Journal:

The American Journal of Pathology

Year:

2007

Language:

english

File:

PDF, 1.28 MB

english, 2007

14

Mitigation of diabetes-related complications in implanted collagen and elastin scaffolds using matrix-binding polyphenol

James P. Chow, Dan T. Simionescu, Harleigh Warner, Bo Wang, Sourav S. Patnaik, Jun Liao, Agneta Simionescu

Journal:

Year:

2013

Language:

english

File:

PDF, 3.53 MB

english, 2013

15

Assembly and Testing of Stem Cell-Seeded Layered Collagen Constructs for Heart Valve Tissue Engineering

Tedder, Mary E., Simionescu, Agneta, Chen, Joseph, Liao, Jun, Simionescu, Dan T.

Journal:

Tissue Engineering Part A

Year:

2011

Language:

english

File:

PDF, 1.78 MB

english, 2011

16

Janus magnetic cellular spheroids for vascular tissue engineering

Mattix, Brandon M., Olsen, Timothy R., Casco, Megan, Reese, Laura, Poole, John T., Zhang, Jing, Visconti, Richard P., Simionescu, Agneta, Simionescu, Dan T., Alexis, Frank

Journal:

Year:

2014

Language:

english

File:

PDF, 3.13 MB

english, 2014

17

The roles of various metabolic enzymes in diabetic cardiomyopathy—in vivo and in vitro approach

Larrew, Thomas, Chow, James, Schulte, Jason, Simionescu, Dan, Simionescu, Agneta

Journal:

Cardiovascular Pathology

Year:

2013

Language:

english

File:

PDF, 53 KB

english, 2013

18

The Acellular Myocardial Flap: A Novel Extracellular Matrix Scaffold Enriched with Patent Microvascular Networks and Biocompatible Cell Niches

Schulte, Jason B., Simionescu, Agneta, Simionescu, Dan T.

Journal:

Tissue Engineering Part C Methods

Year:

2013

Language:

english

File:

PDF, 2.25 MB

english, 2013

19

Lectin and antibody-based histochemical techniques for cardiovascular tissue engineering

Simionescu, Agneta, Tedder, Mary E, Chuang, Ting-Hsien, Simionescu, Dan T

Journal:

Journal of Histotechnology

Year:

2011

Language:

english

File:

PDF, 523 KB

english, 2011

20

Influence of Clinically Relevant Mechanical Forces on Vascular Smooth Muscle Cells Under Chronic High Glucose: An In Vitro Dynamic Disease Model

Chawla, Varun, Simionescu, Agneta, Langan, Eugene M., LaBerge, Martine

Journal:

Annals of Vascular Surgery

Year:

2016

Language:

english

File:

PDF, 2.64 MB

english, 2016

21

Biochemical Pathways of Tissue Degeneration in Bioprosthetic Cardiac Valves; The Role of Matrix Metalloproteinases

SIMIONESCU, AGNETA, SIMIONESCU, DAN, DEAC, RADU

Journal:

Year:

1996

File:

PDF, 590 KB

1996

22

Stabilized collagen and elastin-based scaffolds for mitral valve tissue engineering

Deborde, Christopher, Simionescu, Dan Teodor, Wright, Cristopher, LIAO, JUN, Sierad, Leslie Neil, SIMIONESCU, AGNETA

Journal:

Tissue Engineering Part A

Year:

2016

Language:

english

File:

PDF, 946 KB

english, 2016

23

Bioreactor conditioning of valve scaffolds seeded internally with adult stem cells

Kennamer, Allison, Sierad, Leslie, Pascal, Richard, Rierson, Nicholas, Albers, Christopher, Harpa, Marius, Cotoi, Ovidiu, Harceaga, Lucian, Olah, Peter, Terezia, Preda, Simionescu, Agneta, Simionescu,

Journal:

Tissue Engineering and Regenerative Medicine

Year:

2016

Language:

english

File:

PDF, 2.28 MB

english, 2016

24

Immunomodulatory effects of adipose tissue-derived stem cells on elastin scaffold remodeling in diabetes

Chow, James P., Simionescu, Dan T., Carter, Anna L., Simionescu, Agneta

Journal:

Tissue Engineering and Regenerative Medicine

Year:

2016

Language:

english

File:

PDF, 3.36 MB

english, 2016

25

Challenges in vascular tissue engineering for diabetic patients

Dhulekar, Jhilmil, Simionescu, Agneta

Journal:

Acta Biomaterialia

Year:

2018

Language:

english

File:

PDF, 1.99 MB

english, 2018

26

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || TGF-β Activation and Signaling in Angiogenesis

Simionescu, Dan, Simionescu, Agneta

Year:

2017

Language:

english

File:

PDF, 3.01 MB

english, 2017

27

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Antiangiogenic Therapy for Hepatocellular Carcinoma

Simionescu, Dan, Simionescu, Agneta

Year:

2017

Language:

english

File:

PDF, 1.26 MB

english, 2017

28

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Therapeutic Angiogenesis: Foundations and Practical Application

Simionescu, Dan, Simionescu, Agneta

Year:

2017

Language:

english

File:

PDF, 2.59 MB

english, 2017

29

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Anti-VEGF Therapy in Cancer: A Double-Edged Sword

Simionescu, Dan, Simionescu, Agneta

Year:

2017

Language:

english

File:

PDF, 3.86 MB

english, 2017

30

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Angiogenesis-Related Factors in Early Pregnancy Loss

Simionescu, Dan, Simionescu, Agneta

Year:

2017

Language:

english

File:

PDF, 2.84 MB

english, 2017

31

Inflammation in Cardiovascular Tissue Engineering: The Challenge to a Promise: A Minireview

Simionescu, Agneta, Schulte, Jason B., Fercana, George, Simionescu, Dan T.

Journal:

International Journal of Inflammation

Year:

2011

Language:

english

File:

PDF, 1.21 MB

english, 2011

32

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || VEGF-Mediated Signal Transduction in Tumor Angiogenesis

Simionescu, Dan, Simionescu, Agneta

Year:

2017

Language:

english

File:

PDF, 3.70 MB

english, 2017

33

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Angiogenesis Meets Skeletogenesis: The Cross-Talk between Two Dynamic Systems

Simionescu, Dan, Simionescu, Agneta

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

34

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Tumor Angiogenesis: A Focus on the Role of Cancer Stem Cells

Simionescu, Dan, Simionescu, Agneta

Year:

2017

Language:

english

File:

PDF, 3.85 MB

english, 2017

35

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Corneal Angiogenesis: Etiologies, Complications, and Management

Simionescu, Dan, Simionescu, Agneta

Year:

2017

Language:

english

File:

PDF, 5.15 MB

english, 2017

36

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Hypoxia, Angiogenesis and Atherogenesis

Simionescu, Dan, Simionescu, Agneta

Year:

2017

File:

PDF, 2.72 MB

2017

37

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Platelet Lysate to Promote Angiogenic Cell Therapies

Simionescu, Dan, Simionescu, Agneta

Year:

2017

Language:

english

File:

PDF, 4.84 MB

english, 2017

38

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Vascular Repair and Remodeling: A Review

Simionescu, Dan, Simionescu, Agneta

Year:

2017

Language:

english

File:

PDF, 3.14 MB

english, 2017

39

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Platelet Lysate to Promote Angiogenic Cell Therapies

Simionescu, Dan, Simionescu, Agneta

Year:

2017

File:

PDF, 4.84 MB

2017

40

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Vascular Repair and Remodeling: A Review

Simionescu, Dan, Simionescu, Agneta

Year:

2017

File:

PDF, 3.14 MB

2017

41

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Coronary Collateral Growth: Clinical Perspectives and Recent Insights

Simionescu, Dan, Simionescu, Agneta

Year:

2017

File:

PDF, 2.50 MB

2017

42

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Pathogenic Angiogenic Mechanisms in Alzheimer's Disease

Simionescu, Dan, Simionescu, Agneta

Year:

2017

File:

PDF, 1.47 MB

2017

43

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Novel Methods to Study Angiogenesis Using Tissue Explants

Simionescu, Dan, Simionescu, Agneta

Year:

2017

File:

PDF, 9.28 MB

2017

44

Integrins Î±4Î²1 and Î±VÎ²3 are Reduced in Endothelial Progenitor Cells from Diabetic Dyslipidemic Mice and May Represent New Targets for Therapy in Aortic Valve Disease

Filippi, Alexandru, Constantin, Alina, Alexandru, Nicoleta, Voicu, Geanina, Constantinescu, Cristina Ana, Rebleanu, Daniela, Fenyo, Madalina, Simionescu, Dan, Simionescu, Agneta, Manduteanu, Ileana, G

Journal:

Cell Transplantation

Year:

2020

File:

PDF, 475 KB

2020

45

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || MCAM and its Isoforms as Novel Targets in Angiogenesis Research and Therapy

Simionescu, Dan, Simionescu, Agneta

Year:

2017

File:

PDF, 5.45 MB

2017

46

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Role of Notch, SDF-1 and Mononuclear Cells Recruitment in Angiogenesis

Simionescu, Dan, Simionescu, Agneta

Year:

2017

File:

PDF, 2.75 MB

2017

47

Physiologic and Pathologic Angiogenesis - Signaling Mechanisms and Targeted Therapy || Unique Phenotypes of Endothelial Cells in Developing Arteries: A Lesson from the Ductus Arteriosus

Simionescu, Dan, Simionescu, Agneta

Year:

2017

File:

PDF, 3.72 MB

2017

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